Dr. Reddy's Laboratories and Promius Pharma, Announces FDA Approval for TOSYMRA (Sumatriptan Nasal Spray) 10mg, in the U.S. Market (2024)

FAQs

Is sumatriptan nasal spray safe? ›

Sumatriptan has caused serious side effects in some people, especially people who have heart or blood vessel disease. Be sure that you discuss with your doctor the risks as well as the benefits of using this medicine. This medicine is available only with your doctor's prescription.

The nasal spray and injection are used to treat migraines and cluster headaches. The tablets are for migraines only. Sumatriptan is available on prescription. You can also buy packs containing two, 50mg tablets from a pharmacy without a prescription, but only if you have previously been diagnosed with migraines.

A bitter taste was the most commonly reported side effect of sumatriptan nasal spray--reported by 68% (80 out of 118) of the migraineurs.

The nasal spray usually works within 15 minutes. Each spray contains 1 dose (10mg or 20mg of sumatriptan). If your headache improves but then comes back, you can have another dose after 2 hours. If the first dose of sumatriptan does not help, do not take another dose for the same attack.

Zavzpret Is the First FDA-Approved Gepant Nasal Spray for Acute Migraine. Zavegepant is a type of migraine medication called a gepant. Gepants work to block CGRP, a protein that carries pain signals along nerves that are involved in generating the headache pain associated with migraine.

You may experience pressure, tightness, or pain in your chest, neck, or jaw after taking a dose of sumatriptan. In most cases, this is temporary and unrelated to any heart problems. But don't ignore sudden or intense chest pain since it could be a sign of something more serious.

Sumatriptan has been available in Australia since the early 1990s. Currently, it is only available in Australia as an oral tablet or fast disintegrating tablet (as of February 2024). It was previously available as a nasal spray and injection, however these formulations have been discontinued by the manufacturer.

Zolmitriptan nasal spray is used to treat acute migraine headaches in adults and children 12 years of age and older. It is not used to prevent migraine headaches and is not used for cluster headaches. Zolmitriptan works in the brain to relieve the pain from migraine headaches.

You shouldn't take sumatriptan oral tablets on a regular daily basis. This drug can't prevent migraine. You should only take this medication when you need to treat a migraine headache. Don't take sumatriptan oral tablets on more than 4 days in any 30-day period.

Why is sumatriptan restricted? ›

This medicine may increase your risk of having abnormal heart rhythm, heart attack, angina, or stroke. This is more likely to occur if you or a family member already has heart disease, if you have diabetes, high blood pressure, high cholesterol, or if you smoke.

There are some medicines that may affect the way sumatriptan works. Tell your doctor if you're taking: other migraine or headache medicines (including ergotamine and other triptans) antidepressants, including SSRIs (selective serotonin reuptake inhibitors) or MAOIs (monoamine oxidase inhibitors)

Saline sprays provide gentle relief from congestion while moisturizing your nasal passages, and they're also safe for frequent use. Dr. Trenkle likes nasal sprays that contain xylitol because they have a cleansing effect, reducing the adherence of bacteria and irritants in the nasal passages.

The benefits of nasal spray is that it takes effects faster and enters your blood stream more directly than tablets. The 20 mg nasal spray works in about 15 minutes, making it twice as fast as a 100 mg dose of the tablet.

Use of sumatriptan is not recommended in elderly patients with kidney problems, heart or blood vessel disease, or high blood pressure, and should not be used by elderly patients with liver problems.